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We've found that this on-label versus off-label distinction is the single biggest barrier patients face

GLP-1 receptor agonists Primary mechanism(s) of action Increase glucose-dependent insulin secretion, reduce post-prandial glucagon, and delay gastric emptying (resulting in reduced after meal glucose levels and increased satiety) Examples Exenatide (Byetta 10 mcg Pen, Byetta 5 mcg Pen, Bydureon BCise 2 mcg Pen) Dosage Immediate release (Byetta) Initial: 5 mcg subcutaneous injection twice daily a maximum of 60 minutes before morning and evening meals, or before the two main meals of the day Maximum: 10 mcg subcutaneous injection twice daily a maximum of 60 minutes before morning and evening meals, or before the two main meals of the day Extended release (Bydureon BCise) Initial: 2 mg subcutaneous injection once weekly Maximum: 2 mg subcutaneous injection weekly Lixisenatide (Adlyxin) Short-acting Dosage Initial: 10 mcg subcutaneous injection once daily, up to one hour before the first meal of the day, for 14 days

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The medication is HSA/FSA eligible, making it accessible to more patients pursuing weight loss without insurance barriers

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1,600-calorie plan (common target for women) Breakfast (400 calories, 35g protein): Protein smoothie with 1 scoop whey protein, 1 cup unsweetened almond milk, 1 banana, 1 tablespoon peanut butter, handful of spinach